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中文
The transgene contains the following elements: a 6,756 bp DNA fragment containing the putative Per1 promoter sequence and the 5'-untranslated region, which encompasses exon 1 and part of exon 2, a modified Kcnma1 cDNA where arginine codon 207 was changed to glutamine (p.R207Q), and hemoglobin beta poly(A) signal sequences. This is a fast-activating gain-of-function mutation. (J:191740)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
