这个转基因包含了以下组件:Igf2启动子3型(Rr146,来自chr7:142211218位置的162bp上游至exon3/替代exon1的74bp5'UTR),来自H19下游的Igf2增强子,以及荧光素酶报告基因和SV40的poly(A)信号序列。多条独立的转基因品系被构建。增强子驱动在肝脏中的表达。(来源:J:334634)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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