通过CRISPR/Cas9技术,将编码sCre(自剪切Cre)的cDNA,连接到ERT2后,再配以木鼠的后转录调控元件和polyadenylation序列,这些序列被插入到了Col1a2基因的起始翻译密码子处。(来源:J:309164)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
插入
--
1
18
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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