通过CRISPR/Cas9技术,构建了CrexER(Cre-rox-ER-rox),它由插入的两个rox序列围绕ERT2编码的cDNA实现,该cDNA替换Mki67基因的终止密码子,通过2A自切肽序列以本底Mki67基因后随。来源:(J:303771, J:339117)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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