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中文
使用携带Rr253em3Kmm NFIL3C/EBP结合位点1缺失等位基因的囊胚，针对位于大约165kb上游的Zeb2增强子的位点2和3，通过sgRNAs(目标序列是ATTTTTGCAACCCCCCAAAAA和CCGGTGACACACACTGCTCA)以及ssODN模板(TGGGGGAATGAATCATCAAAATAACCGGTGGAAAACAAGCTAGATCTGAGTTGAGCAGTGTGTGTCACCGGCTGGTGGAATTTTTAGAAAGGCAGCAGTTTGGGCTCATCACTGCGGTTCCTGATTGCACACACCTGTTTGGGGCATGGAGTCGACCTCCCCCCAAAAAGGGGAAACTGAACTCACTGCTCCTCCTGAG)，应用CRISPR/Cas9技术，成功实现了位点1和2的缺失。(来源：J:334296)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
