靶向载体包含一个P2A序列,接着是eGFP/CreERT融合蛋白以及一个FRT引导的PGK-neomycin筛选元件。构建被插入在acathe-scute家族转录因子3(Ascl3)基因的终止密码子上游。随后通过Flp重组酶移除了neo选择性元件。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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