CRISPR/Cas9技术被用来针对含有Rnf133em1Zuk突变(1070bp缺失)的囊胚,目标是删除Rnf148,从而产生Rnf133和Rnf148的双敲除突变基因。这来自文献(J:330415)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK Rnf133em1Zuk/Zuk
Endonuclease-mediated
基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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