(鸡β-actin启动子加上CMV增强子)被用来驱动FLPe基因的表达,该基因带有核定位信号。建立了5个杂交系,其中16号、32号和36号在与含Frt-flanked等位基因的鼠杂交时显示出100%的重组;37号线中有10/11只小鼠表现出重组;16号的2/9只双转基因小鼠和32号的1/8只双转基因小鼠中存在嵌合现象。(来源:J:108559)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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