Klrk1增强子通过CRISPR/Cas9技术,用sgRNAs针对ATAGCCAACATTATACTAGA、AGCACAAGGTGAGTCCTAGG、CTTTCAACTATTATTTAACA和TTCTACAACCATTATGTGGG,实现了靶向编辑,导致chr6:129604124-129604995(GRCm39)区域的缺失(J:333878)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count