Klrc1增强子通过CRISPR/Cas9技术用sgRNAs定向敲除了,具体靶向的是CAGGATAATTATTATGATTG和GAGGCACCGTTCAGATGCAG,结果导致chr6:129657406-129657929(GRCm39)区域的基因发生删除(来源:J:333878)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count