转基因插入包含以下组件:一个SacII-SmaI酶切片段,包含Atoh1下游序列(包括增强子Rr387或E0),其中约411bp的最后部分(子区域B)被删除,Hbb基底启动子,β-半乳糖苷酶报告基因,以及SV40poly(A)信号序列。在背根神经管的胚胎表达被阻断,但在尾状核中仍以微弱形式存在。(来源:J:60854)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA)F1
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插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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