Atoh1增强子Eh2或E3通过CRISPR/Cas9技术,用sgRNAs针对TATGAACTAGAATATTGTATTGG和AACGTATTCAAAGTCAAAGCGGG位点进行了编辑,产生了包含增强子的2519bp缺失,位置在chr6:64774536-64777054(GRCm39)。(引用信息:J:332270, J:333396)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count