Atoh1增强子E1通过CRISPR/Cas9技术,用sgRNAs针对GATTTAGACTCTACACTTGATGG和AGAGATATATTGGAAGGTATAGG进行了靶向,产生了包含增强子的1387bp缺失,位置在chr6:64740810-64742196(GRCm39),参考文献为J:332270。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count