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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Htr6
tm1.1(cre)Smoc
Alias:
5 HT6R
-
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基础信息
表型特征
文献报道
将CreERT2-P2A-EGFP-SV40PA表达载体插入Htr6基因的exon 2,通过同源重组方式,导致了生殖细胞中该位置的基因失活。通过Western blot检测5-HT6R,结果显示为野生型缺失突变体。(引用:J:333280)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
7435295
Not Specified
Endonuclease-mediated
插入
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1
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Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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