在Nprl3基因上游的Hba增强子元件R4被替换成一个由loxP序列和抗氨苄青霉素 resistance gene cassette(neo cassette)组成的失活位点。随后通过Cre介导的重组手段移除了neo cassette(来源:J:259286)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intergenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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