引导RNA被设计用于在基因的催化区域,ENSMUSE00000215695的第7,447,544位碱基对(位置7447544),删除一个碱基(T)。这个变异预测会导致176位氨基酸序列发生改变,并在327位产生一个早停密码子。(来源:J:333090)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
基因内删除
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1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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