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中文
2-4号外显子被替换为一个转录抑制序列(STOP)由loxP座 flank，包含3个编码外显子(2-4)的cDNA序列，93个稀有密码子转换为小鼠基因组中最常见密码子，还包括p.G12D的致癌突变，后面跟着4号内含子的前564bp，以及由FRT座引导的抗氨苄青霉素抗性基因 cassette。通过Flp介导的重组移除neo cassette是必要的，以驱动突变型Kras的表达。(来源：J:328899)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
