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中文
2-4号外显子被替换为一个转录抑制序列(STOP)由loxP座 flank，接着是使用天然稀有密码子的前三个编码外显子(2-4)的cDNA序列，包括p.Q61R的致癌突变，然后是4号内含子的5'564bp，以及由FRT座引导的抗氨苄青霉素抗性基因 cassette。通过Flp介导的重组，删除这个stop cassette是获取低水平突变型Kras表达的必需，因为使用了天然稀有密码子。(来源：J:328899)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
