在一段包含FRT位点、剪接接受器、IRES、β-gal基因、loxP位点、PGK-neo cassette、另一FRT位点以及在exon 2下游插入的第三个loxP位点的构建中,通过同源重组,这些元件被插入到了exon 2的上游,并通过Flp介导的重组,移除了β-gal和neo cassette,使得exon 2成为可删除的(来源:J:319656)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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