CRISPR对exon 25的靶向插入导致了5490和5492位置的G变A,A变C变异,进而造成第1831位氨基酸由 glutamic acid 变为 alanine,即E1831A的替换。(来源:J:332649)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
CBA/J x C57BL/6J
Endonuclease-mediated
核苷酸替换
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部