一个潜在的Fgf23骨骼增强子,位于Fgf23的内含子中,通过CRISPR/Cas9技术用sgRNAs(针对靶点TGTCTCTATTATCTGCAGGG和AAACACAAGAAGTTGAGGGC)进行了修饰,导致了296bp的缺失。(来源:J:281531)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count