在第3外显子上游插入了loxP位点和FRT引导的neo cassette,通过同源重组,又在第6外显子下游插入了loxP位点。同源重组酶介导的重组移除了neo cassette和3-6号外显子。(来源:J:182701, J:311958)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count