在Shc1基因座上插入了两个LoxP序列,位于2到7号外显子周围,以及一个由两个FRT序列 flank 的PKG Neo抗药性基因座。通过与表达翻转酶重组酶的 mice杂交,这个Neo抗药性基因座被剔除了。(来源:J:217881)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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