KOMP向载体PG00072_X_1_H08插入了带有3' loxP末端的lacZ/新霉素抗性元件,这个元件位于exon 4上游一个loxP位点,下游还有一个。通过Flp介导的重组移除了报告和筛选元件,而Cre介导的重组则去除了exon 4。(来源:J:332344)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count