KOMP向载体PG00072_X_1_H08插入了带有3' loxP末端的lacZ/新霉素抗性元件,这个元件位于exon 4上游一个loxP位点,下游还有一个。通过Flp介导的重组移除了报告和筛选元件,而Cre介导的重组则去除了exon 4。(来源:J:332344)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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