PRS区域(染色体11:111446352-111723870,GRCm39),位于Sox9的topologically关联域(TAD)内,包含增强子和调控序列,通过CRISPR/Cas9技术用sgRNAs进行了靶向,导致了这一区域的删除。(来源:J:332097)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Endonuclease-mediated
基因间区删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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