Del(15Rr21-Pvt1)10Fsp

Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.205880Fsp at chr15:61091575-61091576 (GRCm39) and Tn(sb-SBlac)15.188150Fsp at chr15:62602119-62602120 deleted approximately 1.51 Mb and leaves one intact copy of the transposon cassette (in reverse orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancer Rr21, and the Myc and Pvt1 genes. (J:212391)