使用未知来源的TgTn(sb-SBlac)15Fsp转基因小鼠中Sleeping Beauty转座酶对Tn(sb-SBlac)15.179039Fsp转基因小鼠的转座子重新激活,导致转座子在GRCm39染色体15上,位于Myc和Gsdmc之间,具体位置是15:63564154-63564155,以正向插入。转座子包含Sleeping Beauty转座子倒置重复、loxP座、人类β-珠蛋白的HBB最小启动子、lacZβ-半乳糖苷酶报告基因、SV40poly(A)信号序列,以及Sleeping Beauty转座子直接重复。来源:(J:257739)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Transposon induced
转座子插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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