Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
基因编辑小鼠
Del(15Rr316124-Rr313939)2Fsp
Alias:
del(15-17)
Myc
delta15-17
Need animal model construction services?
Click here >>
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
基础信息
表型特征
文献报道
Cre介导的chr15染色体间重组发生在15:63332129-63332130(GRCh39)区间,涉及Tn(sb-SBlac)15.192339Fsp和Tn(sb-SBlac)15.179039Fsp两个元件。这次重组大约移除了259kb,保留了一个反向排列的转座子元件在缺失点。转座子包含Sleeping Beauty转座子的倒置重复、loxP位点、人类β-珠蛋白的HBB启动子、lacZβ-半乳糖苷酶报告基因、SV40的poly(A)信号序列,以及另一个Sleeping Beauty转座子的直接重复。删除序列位于Myc的拓扑关联域(TAD)内,包含了Rr316124、Rr313933、Rr331、Rr307328、Rr332、Rr307330、Rr333和Rr313939等多个Myc增强子。信息来源(J:212391)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
7411151
Not Specified
Transposon induced
Insertion, Intergenic deletion
--
--
--
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部