在ROSA定位插入了以下组件:CAG启动子、一个由loxP序列环绕的STOP cassette、带有3xFLAG标记的Hoxa2 cDNA、一个IRE-SGFP、WPRE元件、bGHpoly(A)以及一个PGK-neomycin cassette。只有在Cre介导去除STOP cassette后,这个等位基因才会表达Hoxa2和EGFP基因。(来源:J:320009)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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