在exon 2的上游插入了loxP位点,接着是带有FRT标签的诺卡因筛选元件,以及在exon 3下游插入了另一个loxP位点。通过flp介导的重组,去除了诺卡因筛选元件,使得exon 2-3区域被标记为可剪接。(来源:J:302917)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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