在第10外显子下游插入了loxP位点,接着是带有FRT标签的诺卡因选择性载体和另一个loxP位点,位于第3外显子上游。通过表达flp重组酶的ES细胞中,通过flp介导的重组移除了诺卡因载体,使得3-10号外显子被标记为可删除。(来源:J:331827)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
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1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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