在HpaI-NcoI限制酶切片段中,包含核心的Ebeta Tcrb增强子的部分被一个700bp的XbaI-EcoRI片段替换,该片段带有Igh的enhancer iEmu(Rr150),同时带有loxP序列标记的诺卡因抗性基因座。随后通过Cre介导的重组,删除了这个neo cassette。(来源:J:34312)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
Insertion, Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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