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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Kcnb1
em2Sesf
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基础信息
表型特征
文献报道
CRISPR/cas9基因编辑用来产生一个导致337个氨基酸缺失的截短蛋白的frameshift等位基因。这个等位基因是一个在创建Kcnb1em1Sesf等位时产生的插入/缺失事件。(来源:J:331047)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
7385068
C57BL/6J
Endonuclease-mediated
基因内删除
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1
4
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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