The targeting construct replaced the coding region with the phosphoglycerol kinase (PGK)-neo expression cassette flanked by a loxP sequence. Cre-mediated recombination removed the selection cassette. (J:325069)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count