Rorc基因的顺式调控元件通过CRISPR/Cas9技术,用sgRNAs针对 ACAAAATGTGCCCGCTCCAC、ACGGAAACGCTGAGCAGGGC 和 GATGATACTGCCGCTATCGT 进行了靶向,产生了1,253bp的缺失。(来源:J:305606)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count