Nppa和Nppb基因通过CRISPR/Cas9技术,使用sgRNAs(针对GACTACATGGCAGATCACCC和GGCCAGTTCAAACGATTTGT)进行了靶向,实现了这两个基因以及位于它们之间的增强子Rr103616的删除,同时也去除了Gm13054长非编码RNA基因的3'端。(引用:J:309962)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NRj
Endonuclease-mediated
Intergenic deletion, Intragenic deletion
--
2
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部