在exon 3前方173bp位置插入了loxP位点,接着插入了带有FRT标记的诺卡因抗性基因和另一个loxP位点,位于exon 3后方150bp。通过flp介导的重组,去除了诺卡因抗性基因,使得exon 3区域可被同源重组剪接掉。(来源:J:330105)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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