Rr284^em1Zllr

This Grem1 limb regulatory region, located in Fmn1 intron 13 [in reference to ENSMUST00000081349], was targeted with sgRNAs (targeting CACCGCCTGTGATCCATCGAATGCC and AAACGGCATTCGATGGATCACAGGC) using CRISPR/Cas9 technology, resulting in an 8.3 kb deletion (chr2:113503131-113511422 GRCm39). (J:312378)