将Shh增强子ZRS或MFCS1(哺乳动物和鱼保守序列1)的位置,位于Lmbr1的第五个内含子中,用等长的1324bp同源冷泉鱼序列(JH127332:522,984-524,307,latCha1)替换,通过sgRNA(靶向AGTACCATGCGTGTGTGTGA)和CRISPR/Cas9技术的质粒DNA模板进行操作。来源:(J:316049)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
Endonuclease-mediated
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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