Gata2基因的内含子增强子通过CRISPR/Cas9技术用sgRNA(靶向TCTCCTGCCGGAGTTTCCTATCCGG)进行了修饰,产生了28bp的缺失( CCTGCCGGAGTTTCCTATCCGGACATCT),这删除了CATCTG的决定性C序列。 (来源:J:295045)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count