在内含子2位置插入了loxp位点,随后在neomycin抗性基因座周围包含了FRT序列,再跟着一个loxp位点在基因下游。通过后续的flp介导重组,去除了neo cassette,形成一个带有2-4号外显子敲除的条件性可操作等位基因。(来源:J:273599)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
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1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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