这些小鼠携带有Sorl1基因第六外显子周围的loxP位点,当与表达Cre重组酶的品系杂交时,这种品系能用于在特定组织中消除Sorl1基因的条件性表达。Sorl1-Flox(2)(库存号NM-CKO-215075)小鼠则携带有Myc基因第五外显子周围的loxP位点(来源:J:238766)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count