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中文
CRISPR/Cas9技术通过非同源重组手段，删除了小鼠Serpina3c基因的2-5号外显子。qPCR结果显示，这种操作在包括棕色脂肪组织(BAT)、阴囊和睾丸白色脂肪组织(WAT)、肝脏和肌肉在内的多种组织中，导致了mRNA表达的丧失。 Western blot分析进一步证实了这些转基因纯合子小鼠阴囊和睾丸WAT中蛋白质表达的缺失。(来源：238766)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
