将一个A IRES-iCre表达座插入到Il13基因的终止密码子位点。该基因编码一个多功能的细胞因子。当与携带loxP座的基因型杂交时,表达cre的细胞中会剔除带有loxP座的基因。这种细胞因子参与免疫调节、炎症反应和造血过程的调控。(来源:J:238766)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
插入
不确定
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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