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这些小鼠体内存在一个由loxP启动子和STOP cassette修饰的区域，阻止了由CAG启动子驱动的ACHE基因的转录。目标突变通过同源重组插入到了Hipp11（H11）位点。当与能产生Cre重组酶的 mice杂交时，ACHE基因会表达。(来源：J:238766)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
