一种SA-2xpolyA-CAG-Loxp-Stop-Loxp人类EZH2基因cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA插件被敲入小鼠的Rosa26位点。这种小鼠可以与表达Cre重组酶的鼠杂交,经Cre重组酶激活后,能够表达人类的EZH2基因。(来源:J:238766)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count