这些小鼠携带有Esr1基因第3外显子周围的loxP位点,当与表达Cre重组酶的纯合品系杂交时,可用于在特定组织中消除Esr1基因的条件性表达。Esr1-Flox(Stock No.NM-CKO-200024)小鼠则携带Esr1基因第4外显子的loxP位点(来源:J:238766)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
插入
不确定
1
4
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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