在Cyp3a57和Cyp3a59之间(包括Cyp3a11, Cyp3a16, Cyp3a25, Cyp3a41, Cyp3a44, Cyp3a57, Cyp3a58-ps, Cyp3a59)的所有基因都被敲除,产生了Cyp3a-KO小鼠(库存号NM-KO-18056)。在Cyp3a57和Cyp3a59之间(包括上述基因以及Cyp3a13)的基因,以及Cyp3a13,一起被敲除,产生了Cyp3a-KO(2)小鼠(库存号NM-KO-190427)。(来源:J:238766)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
基因内删除
不确定
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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