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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Calm1
tm1Smoc
Alias:
Calm1
tm1(Flox-K22R-K95R-K116R)Smoc
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基础信息
表型特征
文献报道
Calm1基因的Exon3被替换成loxp-exon3-6-loxp的序列,其中包含K22R、K95R和K116R的突变。当与表达Cre重组酶的菌株杂交时,这种设计能用于在特定组织中剔除突变Calm1基因的条件性表达。(来源:J:238766)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
7288616
Not Specified
Targeted
单点
不确定
1
4
--
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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