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中文
使用sgRNAs(针对GCCGTTCTTCCTAATGTGCA和GGAAGTGTCAACATCACCAG)，以及两个ssODN模板，通过CRISPR/Cas9技术，在GRCm39的19号染色体33198267和33202330位置插入了loxP序列，目的是围绕位于Rnls内含子4的Pten增强子区域。参考文献：J:320472
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
